Mario Daniel Galigniana

• De Leo SA, Zgajnar NR, Lotufo C, Mazaira GI, Erlejman AG, Galigniana MD (2020) Role of the Hsp90-immunophilin heterocomplex in cancer disease. Current Cancer Therapy Reviews. 16: 19-28.
• Gupta SD, Swapanthi PS, Bhagya D, Federicci F, Mazaira GI, Galigniana MD, Subrahmanyam CVS, Gowrishankar NL, Raghavendra NM (2019) Rational Identification of Hsp90 Inhibitors as Anticancer Lead Molecules by Structure Based Drug Designing Approach. Anticancer Agents in Medicinal Chemistry. Nov 11. doi: 10.2174/1871520619666191111152050. In press.
• Leonardi DB, Anselmino N, Brandani JN, Jaworski FM, Páez AV, Mazaira G, Meiss RP, Nuñez M, Nemirovsky SI, Giudice J, Galigniana M, Pecci A, Gueron G, Vazquez ES, Cotignola J (2019) Heme oxygenase 1 impairs glucocorticoid receptor activity in prostate cancer. International Journal of Molecular Sciences. 20(5). pii: E1006. doi: 10.3390/ijms20051006.
• Daneri-Becerra C, Zgajnar NR, Lotufo MC, Ramos Hryb AB, Piwien-Pilipuk G, Galigniana MD (2019) Regulation of FKBP51 and FKBP52 functions by post-translational modifications. Biochemical Society Transactions. 47:1815-1831.
• Mazaira GI, Galigniana MD (2019) Reconstitution of the steroid receptor heterocomplex. Methods in Molecular Biology. 1966:125-135.
• Mazaira GI, Zgajnar NR, Lotufo CM, Daneri C, Sivils JC, Soto OB, Cox MC, Galigniana MD (2019) Nuclear Receptors: A historical perspective. Vol 5 Nuclear Receptor Research Vol 5, pii: 101320. doi: 10.11131/2018/101320.
• Zgajnar NR, De Leo SA, Lotufo CM, Erlejman AG, Piwien Pilipuk G, Galigniana MD (2019) Molecular mechanisms underlying the biological actions of the Hsp90-binding immunophilins FKBP51 and FKBP52. Biomolecules 9(2). pii: E52. doi: 10.3390/biom9020052.
• Maddela S, Makula A, Galigniana MD, Parambi DGT, Federicci F, Mazaira G, Hendawy OM, Dev S, Mathew GE, Mathew B (2019) Fe3 O4 nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors. Arch Pharm (Weinheim). 2019 Jan;352(1):e1800174. doi: 10.1002/ardp.201800174
• Mazaira GI, Zgajnar NR, Lotufo CM, Daneri C, Sivils JC, Soto OB, Cox MC, Galigniana MD (2018) The nuclear receptor field. A historical overview and future challenges. Nuclear Receptor Research. Vol 5, ID 101320, 21 pages; doi:10.11131/2018/101320
• Mazaira GI, Daneri-Becerra C, Zgajnar NR, Lotufo CM, Galigniana MD (2018) Gene Expression Regulation by Heat-Shock Proteins. The Cardinal Roles of HSF1 and Hsp90. Biochemical Society Transactions 46: 51-65.
• Laiseca JE, Ladelfa MF, Cotignola J, Peche LY, Pascucci FA, Galigniana MD, Schneider C, Monte M (2017) Functional interaction between co-expressed MAGE-A proteins. MageA6 expression induces MageA11 protein stability. PLoS One 12(5):e0178370. doi: 10.1371/journal.pone.0178370
• Daneri-Becerra C, Galigniana MD (2016) Regulatory role of Hsp90 and Hsp90-binding immunophilins in autoimmunity and inflammatory processes of the nervous system. Integrative Molecular Medicine 3: DOI: 10.15761/IMM.1000 S1001.
• Lagadari M, Zgajnar NR, Gallo LI, Galigniana MD (2016) Hsp90-Binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity. Molecular Oncology 10: 1086-1098.
• Michelini F, Bueno CA, Molinari AM, Galigniana MD, Galagovsky LR, Alché LE, Ramirez JA (2016) Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors. Biochimica et Biophysica Acta (General Subjects) 1860:129-139.
• Mazaira GI, Camisay MF, De Leo SA, Erlejman AG, Galigniana MD (2016) Biological relevance of Hsp90-binding immunophilins in cancer development and treatment. International Journal of Cancer 138:797-808.
• Lagadari M, De Leo SA, Camisay MF, Galigniana MD, Erlejman AG (2016) Regulation of NF-B signalling cascade by immunophilins. Current Molecular Pharmacology 9: 99-108.
• Galigniana MD (2016) Editorial: Immunophilins, Protein Chemistry and Cell Biology of a Promising New Class of Drug Targets. Current Molecular Pharmacology 9:3-4.
• Mazaira G, Galigniana MD (2015) Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1. Antiviral Research 122:55-63.
• Sayan Dutta Gupta S, Bommaka MK, Mazaira GI, Galigniana MD, Satya CV, Naryanasamy S, Gowrishankar L, Raghavendra NM (2015) Molecular docking study, synthesis and biological evaluation of Mannich bases as Hsp90 inhibitors. International Journal of Biological Macromolecules 80:253-259.
• Dutta Gupta S, Revathi B., Mazaira GI, Galigniana MD, Subrahmanyam CVS, Gowrishankar NL, Raghavendra NM (2015) 2,4-dihydroxy benzaldehyde derived Schiff bases as small molecule Hsp90 inhibitors: Rational identification of a new anticancer lead. Bioorganic Chemistry 59C:97-105.
• Guy NC, Garcia YA, Sivils JC, Galigniana MD, Cox MB (2015) Functions of the Hsp90-binding FKBP immunophilins. Subcellular Biochemistry 78:35-68.
• Mazaira GI, Erlejman AG, Galigniana MD (2015) Molecular chaperones shape steroid receptor action and pharmacologic strategies. Journal of Cell & Molecular Biology. Vol 1 (1):004.
• Mazaira GI, Lagadari M, Erlejman AG, Galigniana MD (2014) The emerging role of TPR-domain immunophilins in the mechanism of action of steroid receptors. Nuclear Receptor Research, Vol. 1, ID 101094, 17 pages, doi:10.11131/2014/101094. 73. Napimoga MH, Galigniana MD, Migliorini Figueira A.C, Onate SA, Castro-Obregon S (2014) Editorial: Nuclear receptor research, contributions from Latin America, Nuclear Receptor Research, Vol. 1, ID Article ID 101149, 3 pages, doi:10.11131/2014/101149.
• Erlejman AG, De Leo SA, Mazaira GI, Molinari AM, Camisay MF, Fontana V, Cox MB, Piwien-Pilipuk G, Galigniana MD (2014) NF-kB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: A role for peptidyl-prolyl isomerase activity. Journal of Biological Chemistry 289: 26263–26276.
• Erlejman AG, Lagadari M, Harris DC, Cox M, Galigniana MD (2014) Molecular chaperone activity of TPR-domain immunophilins. Current Protein & Peptide Science 15: 205-215.
• Galigniana MD (2014) Editorial: The biology of molecular chaperones−Very complex activities for quite simple proteins. Current Protein & Peptide Science 15: 169-170.
• Dutta Gupta S, Snigdha D, Mazaira GI, Galigniana MD, Subrahmanyam CV, Gowrishankar NL, Raghavendra NM (2014) Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors. Biomedicine & Pharmacotherapy 68:369-376.
• Erlejman AG, Lagadari M, Toneatto J, Piwien-Pilipuk G, Galigniana MD (2014) Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression. Biochimica et Biophysica Acta (Gene Reg Mech) 1839:71-87.
• Toneatto J, Guber S, Charó NL, Susperreguy S, Schwartz J, Galigniana MD, Piwien-Pilipuk G (2013) Dynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by PKA signaling pathway to control gene expression in the process of adipocyte differentiation. Journal of Cell Science 126:5357-5368.
• Molinari A, Machado M, Mazaira G, Erlejman A, Galigniana MD (2013) Molecular basis of mineralo-corticoid receptor action in the nervous system. CNS Neurological Disorders–Drug Targets 12:1163-1174.
• Galigniana MD (2013) Editorial: Steroid-dependent management of biological responses in the nervous system. CNS Neurological Disorders–Drug Targets 12:1143-1145.
• Erlejman AG, Lagadari M, Galigniana MD (2013) Hsp90-binding immunophilins as a potential new platform for drug treatment. Future Medicinal Chemistry 5:591-607.
• Galigniana MD (2013) When the Cell Stress Society International became South American: Meeting report of the IX International Workshop on the Molecular Biology of Stress Responses. Cell Stress & Chaperones 18:3-9.
• Galigniana MD (2012) Steroid receptor coupling becomes nuclear. Chemistry & Biology 19:662-663.
• Galigniana NM, Ballmer LT, Toneatto J, Erlejman AG, Lagadari M, Galigniana MD (2012) Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51. Journal of Neurochemistry 122: 4-18.
• Quintá HR, Galigniana MD (2012) The neuroregenerative mechanism mediated by the Hspp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation. Bristish Journal of Pharmacology. 166:637-49.
• Brookes JC, Galigniana MD, Harker AH, Stoneham AM, Vinson GP (2012) System among the corticosteroids: Specificity and molecular dynamics. Journal of the Royal Society Interface 9:43-53.
• Quintá HR, Galigniana NM, Daneri-Becerra CR, Erlejman AG, Lagadari, M, Galigniana MD (2011) Housekeeping role of heat-shock proteins and immunophilins in the organization of cytoskeleton involves early recruitment to nascent filaments. Cellular Signalling 23:1907-1920.
• Gallo LI, Lagadari M, Piwien Pilipuk G, Galigniana MD. (2011) TPR-domain immunophilin FKBP51 is a novel mitochondrial factor with antiapoptotic function. Journal of Biological Chemistry 286:30152-60
• Sivils J, Storer CL, Galigniana MD, Cox MB (2011) Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52). Currents Opinion in Pharmacology. 11:314-319.
• Storer CL, Dickey C, Galigniana MD, Rein T, Cox M (2011) Roles for the 51-kDa and 52-kDa FK506-binding proteins in signaling and disease. Trends in Endocrinology & Metabolism 22:481-490.
• Quinta HR, Maschi D, Gomez-Sanchez C, Piwien-Pilipuk G, Galigniana MD (2010) Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth. Journal of Neurochemistry. 115:716-734.
• Galigniana MD, Echeverría PC, Erlejman AG, Piwien-Pilipuk G (2010) Role of molecular chaperones and TPR-domain proteins in the cytoplasmic transport of steroid receptors and their passage through the nuclear pore. Nucleus 1:299-308.
• Galigniana MD, Erlejman AG., Monte M, Gomez-Sanchez C, Piwien-Pilipuk G (2010) The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events. Molecular & Cellular Biology 30:1285-1298.
• Echeverría PC, Mazaira G, Erlejman A, Gómez Sánchez C, Piwien Pilipuk G, Galigniana MD (2009) Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta. Molecular & Cellular Biology 29: 4788-4797.
• Colo G, Rubio M, Nojek I, Echeverría PC, Alvarado CV, Nahmod VE, Galigniana MD, Costas MA (2008) The p160 nuclear receptor co-activator RAC3 exerts an anti-apoptotic role through a cytoplasmatic action. Oncogene 27:2430-2444.
• Gallo LI, Ghini A, Piwien G, Galigniana MD (2007) Differential recruitment of tetratricopeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity. Biochemsitry 46:14044-14057.
• Piwien Pilipuk G, Vinson GP, Gomez Sanchez C, Galigniana MD (2007) Evidence for an NL1-independent nuclear translocation of the mineralocorticoid receptor in permeabilized cells. Biochemistry 46:1389-1397.
• Salatino M, Beguelin W, Peters MG, Carnevale R, Proietti CJ, Galigniana MD, Vedoy CG, Schillaci R, Charreau EH, Sogayar MC, Elizalde PV (2006) Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation. Oncogene 25:7723-7739.
• Aviezer-Hagai K, Skovorodnikova J, Galigniana MD, Farchi PO, Efrat Y, von Koskull-Doring P, Ohad N, Breiman A (2007) Arabidopsis immunophilins ROF1 (AtFKBP62) and ROF2 (AkFKBP65) exhibit tissue specificity, are heat-stress induced, and bind hsp90. Plant Molecular Biology 63:237-255.
• Presman DM, Hoijman E, Ceballos NR, Galigniana MD, Pecci A (2006) Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes. Endocrinology 147:5452-5459.
• Harrell JM, Murphy PJM, Morishima Y, Chen H, Mansfield JF, Galigniana MD, Pratt WB (2004) Evidence for glucocorticoid receptor transport on microtubules by dynein. Journal of Biological Chemistry 279:54647-54654.
• Galigniana MD, Morishima Y, Gallay PA, Pratt WB (2004) Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex. Journal of Biological Chemistry 279:55754-55759.
• Murphy PJ, Galigniana MD, Harrell JM, Lujngman M, Pratt WB (2004) Pifithrin-α is a specific inhibitor of p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. Journal of Biological Chemistry 279:30195-30201.
• Galigniana MD, Harrell JM, O’Hagen HM, Ljungman M, Pratt WB (2004) Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus. Journal of Biological Chemistry 279: 22483-22489.
• Pratt WB, Galigniana MD, P.Murphy (2004) Role of molecular chaperones in steroid receptor action. Essays in Biochemistry 40: 41-58.
• Galigniana MD, Piwien Pilipuk G (2004) Activation of the ligand-mineralocorticoid receptor functional unit by ancient, classical, and novel ligands. Structure-activity-relationship. Vitamins & Hormones 69: 31-68.
• Pratt WB, Galigniana MD, Harrell JM, DeFranco D (2004) Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement. Cellular Signalling 16: 857-872.
• Galigniana MD, Piwien Pilipuk G, Kanelakis KC, Burton G, Lantos CP (2004) Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of novel pregnanesteroids . Molecular & Cellular Endocrinology 217: 167-179.
• Galigniana MD, Harrell JM, Housley PR, Patterson C, Fisher SK, W.Pratt (2004) Retrograde transport of the GR in neurites requires dynamic assembly of complexes with hsp90 and is linked to the CHIP component of the proteosome. Molecular Brain Research 123:27-36.
• Piwien Pilipuk G, Galigniana MD, Schwartz J (2003) Subnuclear localization of C/EBPβ is regulated by growth hormone and dependent on MAPK. Journal of Biological Chemistry 278:35668-35677.
• Murphy PJ, Morishima Y, Simons S, Mansfield JF, Galigniana MD, Pratt WP (2003) Visualization and mechanism of assembly of a glucocorticoid receptor-hsp70 complex primed by subsequent hsp90-dependent opening of the steroid binding cleft. Journal of Biological Chemistry 278:34764-34773.
• Ríos MC, Mazzetti MB, Galigniana MD, Aldonatti C, Tomio JM, San Martín L (2002) The decrease in uroporphyrinogen activity induced by ethanol predisposes the development of porphyria and accelerates xenobiotic-triggered porphyria, regardless of hepatic damage. Brazilian Journal of Medical & Biological Research 11:1273-1283.
• Galigniana MD, Harrell JM, Murphy JP, Radanyi C, Renoir JM, Zhang M, Pratt WB (2002) Binding of hsp-90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain. Biochemistry 41:13602-13619.
• Piwien Pilipuk G, Kanelakis K, Ghini A,Lantos C, Litwack G,Burton G, Galigniana MD (2002) Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxido-progesterone. Biochimica et Biophysica Acta (Mol Cell Res) 1589, 31-48.
• Vicent GP, Pecci A, Ghini AA, Piwien Pilipuk G, Galigniana MD (2002) Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific biological responses. Experimental Cell Research 276:142-154 – published in the “Highlight Section”-
• Piwien Pilipuk G, Ayala A, Machado A, Galigniana MD (2002) Impairment of mineralocorticoid receptor-dependent biological response by oxidative stress and ageing. Correlation with post-translational modification of MR and decreased ADP-ribosylatable level of EF-2 in kidney cells. Journal of Biological Chemistry 277, 11896-11903.
• Harrell JM, Kurek I, Breiman A, Radanyi C, Renoir JM, Pratt WB, Galigniana MD (2002) All of the protein interactions that link steroid receptor-hsp90-immunophilin heterocomplexes to cytoplasmic dynein are common to plant and animal cells. Biochemistry 41, 5581-5587.
• Piwien-Pilipuk G, Kanelakis KC, Galigniana MD (2002) Correlation between pregnanesteroid conformation, receptor affinity and antinatriuretic effect. European Journal of Pharmacology 454:131-143.
• Galigniana MD, Radanyi C, Renoir JM, Housley PR, Pratt WB Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. Journal of Biological Chemistry 276, 14884-14889.
• Murphy J, Kanelakis KC, Morishima Y, Galigniana MD, Pratt WB (2001) Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate. Journal of Biological Chemistry 276:30092-30098.
• Houshyar H, Galigniana MD, Pratt WB, Woods JH (2001) Chronic morphine treatment alters pituitary-adrenal negative feedback sensitivity and downregulates glucocorticoid receptors in the rat brain. Journal of Neuroendocrinology 13:875-886.
• Galigniana MD, Vicent GP, Piwien Pilipuk G, Burton G, Lantos CP (2000) Molecular mechanism of action of the potent sodium-retaining steroid 11,19-oxidoprogesterone. Molecular Pharmacology 58:58-70.
• Kanelakis KC, Murphy P, Morishima Y, Toft D, Galigniana MD, Pratt WB (2000) Hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1. Biochemistry 39:14314-14321.
• Piwien Pilipuk G, Galigniana MD (2000) Oxidative stress induced by L-buthionine-(S,R)-sulfoximine, a selective inhibitior of the glutathione metabolism, inhibits the mouse kidney mineralocorticoid receptor function. Biochimica et Biophysica Acta (Mol Cell Res) 1495:263-280.
• Galigniana MD (2000) Functional regulation of corticosteroid receptors by phosphorylation and redox potential. Current Topics in Steroid Research 3:1-22.
• Pratt WB, Silverstein AM, Galigniana MD (1999) A model for the cytoplasmic trafficking of signal proteins involving the hsp90-binding immunophilins and p50cdc37. Cellular Signalling 11:839-851.
• Silverstein AM, Galigniana MD, Kanelakis KC, Radanyi C, Renoir JM, Pratt WB (1999) Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein. Journal of Biological Chemistry 274:36980-36986 (1999).
• Kanelakis KC, Morishima Y, Dittmar K, Galigniana MD, Pratt WB (1999) Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery. Journal of Biological Chemistry 274:34134-34140.
• Galigniana MD, Piwien Pilipuk G (1999) Comparative inhibition by hard and soft metal ions on steroid binding capacity of cross-linked renal mineralocorticoid receptor. Biochemical Journal 341:585-592.
• Galigniana MD, Housley PR, DeFranco D, Pratt WB (1999) Inhibition of the GR nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton. Journal of Biological Chemistry 274:16222-16227.
• Vicent GP, Pecci A, Ghini A, Piwien Pilipuk G, Burton G, Lantos CP, Galigniana MD (1999) The gluco-corticoid properties of the synthetic steroid pregna-1,4-diene-11ß-ol-3,20-dione (ΔHOP) are not entirely correlated with the steroid receptor binding to the glucocorticoid receptor. Molecular & Cellular Endocrinology 149:207-219.
• Galigniana MD, Piwien Pilipuk G, Assreuy J (1999) Inhibition of glucocorticoid receptor by nitric oxide. Molecular Pharmacology 55:317-323.
• Galigniana MD, Scruggs J, Harrington J, Welsh J, Carter-Su C, Housley P, Pratt W (1998) Hsp90-dependent (geldanamycin inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton. Molecular & Cellular Endocrinology 12:1903-1913.
• Piwien Pilipuk G, Galigniana MD (1998) Tautomycin inhibits phosphatase-dependent transformation of the rat kidney mineralocorticoid receptor. Molecular & Cellular Endocrinology 144:119-130.
• Galigniana MD (1998) Native rat kidney mineralocorticoid receptor is a phosphoprotein whose transformation to a DNA-binding form is induced by phosphatases. Biochemical Journal 333:555-563.
• Vicent GP, Burton G, Ghini A, Lantos CP, Galigniana MD (1998) Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives. Journal of Steroid Biochemistry & Molecular Biology 66:211-216.
• Dittmar KD, Banach M, Galigniana MD, Pratt WB (1998) The role of DnaJ-like proteins in the glucocorticoid receptor-hsp90 heterocomplex assembly by the reconstituted hsp90-p60-hsp70 foldosome complex. Journal of Biological Chemistry 273:7358-7366.
• Vicent GP, Monteserín MC, Veleiro AS, Burton G, Lantos CP, Galigniana MD (1997) 21-OH-6,19-oxido-progesterone: a novel synthetic steroid with specific anti-glucocorticoid properties. Molecular Pharmacology 52:749-753.
• Czar MJ, Galigniana MD, Silverstein AM, Pratt WB (1997) Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus. Biochemistry 36:7776-7785.
• Silverstein AM, Galigniana MD, Chen MS, Owens-Grillo JK, Chinkers M, Pratt WB (1997) Protein phosphatase 5 is a major component of glucocorticoid receptor-hsp90 complexes with properties of an FK-506-binding immunophilins. Journal of Biological Chemistry 272:16224-16230.
• Galigniana MD, Vicent GP, Burton G, Lantos CP (1996) Features of the shuttle pair 11ß-hydroxy-progesterone/11-ketoprogesterone. Steroids 62:358-364.
• Galigniana MD (1996) Stability study on renal type I mineralocorticoid receptor. Life Sciences 59:511-21.
• Burton G, Galigniana MD, de Lavallaz S, Brachet-Cota A, Sproviero E, Ghini A, Lantos, CP, Damasco MC (1995) Sodium-retaining activity of some natural and synthetic 21-deoxysteroids. Molecular Pharmacology 47:535-543.
• Galigniana MD, Vicent GP, Lantos CP, Burton G (1994) 11,19-oxidoprogesterone: A potent sodium retaining steroid binding to an alternative site in rat kidney type I receptor. European Journal of Endocrinology 130: 260.
• Galigniana MD, Vicent GP, Lantos CP, Burton G (1993) Ligand properties of 11,19-oxidoprogesterone. A preliminary report. Journal of the Argentine Chemical Society 81:333-340.

AWARDS

2019: Distinguished Fellow of the Cell Stress Society International.

2016: Honorary Member of the Athens Institute for Education and Research.

2013: Elsevier Award in Appreciation of Scientific Excellence, VIII International Meeting of the Society for Free Radical Biology and Medicine, Buenos Aires.

2011: Cherni Foundation (Accesit Award), Argentine Society for the Clinical Investigation (best interdisciplinary research).

2011: University of Buenos Aires, International Recognition Award.

2010: Guggenheim Foundation, Latin America and Caribbean Guggenheim Award, Project: Role of the hsp90-binding immunophilin FKBP51 in apoptosis and tumor progression.

2003: Young Investigator Award, International Aldosterone Society, Philadelphia, USA.

2005: Leloir Foundation, Institutional Award.

2006: Antorchas Foundation, Original Research Award.

Travel Awards: Endocrine Society (San Francisco ‘96, San Diego ‘99 y New Orleáns ‘04); Aldosterone Society (Londres ‘03 y New Orleans ‘04); Cell Stress Soc Intl (Budapest ‘97, Evanston ’98 y Chicago ‘00).