Education and Professional Training
- M.D, College of Medicine, Taipei Medical University, Taiwan.
- Ph.D, Institute of Biomedical Engineering, National Yang Ming University, Taiwan.
- Residency of Department of Radiation Oncology at Mackay Memorial Hospital, Taipei.
- Palliative care & Hospice Training. at Mackay Memorial Hospital., Taipei.
- Fellowship at University of Los Angeles, California USA.
Professional Experience
- 1996-1998: Attending physician in the Department of Radiation Oncology at Mackay Memorial Hospital, Taipei.
- 1996-1998: Attending physician in Hospice at Mackay Memorial Hospital.
- 1998-2011: Director of Department of Radiotherapy and Oncology, Wanfang Medical Center.
- 1998: Attending physician in Department of Radiation Oncology at Taipei Medical, University Hospital.
- 2005 - 2008: Director of Cancer Center, Wanfang Medical Center.
- 2011: Director of Department of Radiation Oncology, Shuang-Ho Hospital.
Research Interests
- Cancer biology.
- Stereotactic Radiotherapy.
- Radiation dosimetry.
- Hospice, Cancer terminal care.
Recent Publications
- Wang CH, Lin CY, Chen JS, Ho CL, Rau KM, Tsai JT, Chang CS, Yeh SP, Cheng CF, Lai YL. Karnofsky Performance Status as A Predictive Factor for Cancer-Related Fatigue Treatment with Astragalus Polysaccharides (PG2) Injection-A Double Blind, Multi-Center, Randomized Phase IV Study. Cancers (Basel). 2019 Jan 22;11(2). (SCI)
- Liu SC, Huang CM, Bamodu OA, Lin CS, Liu BL, Tzeng YM, Tsai JT, Lee WH, Chen TM. Ovatodiolide suppresses nasopharyngeal cancer by targeting stem cell-like population, inducing apoptosis, inhibiting EMT and dysregulating JAK/STAT signaling pathway. Phytomedicine. 2018 May 8;56:269-278. (SCI)
- Lin JC, Tsai JT, Chao TY, Ma HI, Liu WH. The STAT3/Slug Axis Enhances Radiation-Induced Tumor Invasion and Cancer Stem-like Properties in Radioresistant Glioblastoma. Cancers (Basel). 2018 Dec 13;10(12). (SCI)
- Lin JC, Tsai JT, Chao TY, Ma HI, Chien CS, Liu WH. MSI1 associates glioblastoma radioresistance via homologous recombination repair, tumor invasion and cancer stem-like cell properties. Radiother Oncol. 2018 Nov;129(2):352-363. (SCI)
- Lin JC, Tsai JT, Chou YC, Li MH, Liu WH. Compared with intensity-modulated radiotherapy, image-guided radiotherapy reduces severity of acute radiation-induced skin toxicity during radiotherapy in patients with breast cancer. Cancer Med. 2018 Aug;7(8):3622-3629. (SCI)
- Liu M, Bamodu OA, Kuo KT, Lee WH, Lin YK, Wu ATH, M H, Tzeng YM, Yeh CT, Tsai JT. Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/[Formula: see text]-Catenin Signaling. Am J Chin Med. 2018;46(4):891-910. (SCI)
- Chang HL, Chen HA, Bamodu OA, Lee KF, Tzeng YM, Lee WH, Tsai JT. Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro. Toxicol In Vitro. 2018 Sep;51:74-82. (SCI)
- Chen YJ, Kuo CC, Ting LL, Lu LS, Lu YC, Cheng AJ, Lin YT, Chen CH, Tsai JT, Chiou JF. Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer. Oncology Letters. 2018 Feb; 15(2): 1789–1798. (SCI)
- Tsai YC, Kuo CY, Lin JW, Yang ST, Lai SC, Tsai JT. Gamma Knife Perfexion® radiosurgery and endo diode laser thermotherapy for choroidal melanoma with technical analysis: A case report. Oncology Letters. 2018 Jan; 15(1): 91–98. (SCI)
- Li MH, Huang SF, Chang CC, Lin JC, Tsai JT. Variations in dosimetric distribution and plan complexity with collimator angles in hypofractionated volumetric arc radiotherapy for treating prostate cancer. Journal of Applied Clinical Medical Physics. 2018 Mar;19(2):93-102. (SCI)
- Li MH, Tsai JT, Ting LL, Lin JC, Liu YC. Comparison of Thoracic Radiotherapy Efficacy Between Patients With and Without EGFR-mutated Lung Adenocarcinoma. In Vivo. 2018 Jan-Feb;32(1):203-209.
- Cheng HW, Lo WL, Kuo CY, Su YK, Tsai JT, Lin JW, Wang YJ, Pan DH. Forward treatment planning techniques to reduce the normalization effect in Gamma Knife radiosurgery. J Appl Clin Med Phys. 2017 Nov;18(6):114-122. doi: 10.1002/acm2.12193. Epub 2017 Sep 27. (SCI)
- Lee HL, Kuo CC, Tsai JT, Chen CY, Wu MH, Chiou JF. Magnetic Resonance-Guided Focused Ultrasound Versus Conventional Radiation Therapy for Painful Bone Metastasis: A Matched-Pair Study. Journal of Bone & Joint Surgery – American. 2017;(99):1572–1578.(SCI)
- Kuo CY, Tsai YC, Shiau AC, Cheng HW, Yu HW, Su YK, Tsai JT. Evaluation of Clinical Application and Dosimetric Comparison of Treatment Plans of Gamma Knife and CyberKnife in Treating Arteriovenous Malformations. Stereotact Funct Neurosurg. 2017;95(3):142-148. (SCI)
- Lin JC, Tsai JT, Chou YC, Li MH, Liu WH.Compared with intensity-modulated radiotherapy, image-guided radiotherapy reduces severity of acute radiation-induced skin toxicity during radiotherapy in patients with breast cancer. Cancer Med. 2018 Jul 3.(SCI)
- Liu M, Bamodu OA, Kuo KT, Lee WH, Lin YK, Wu ATH, M H, Tzeng YM, Yeh CT, Tsai JT. Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/[Formula: see text]-Catenin Signaling. Am J Chin Med. 2018;46(4):891-910.
- Chang HL, Chen HA, Bamodu OA, Lee KF, Tzeng YM, Lee WH, Tsai JT. Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro.
- Chen YJ, Kuo CC, Ting LL, Lu LS, Lu YC, Cheng AJ, Lin YT, Chen CH, Tsai JT, Chiou JF. Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer. Oncology Letters. 2018 Feb; 15(2): 1789–1798. (SCI)
- Tsai YC, Kuo CY, Lin JW, Yang ST, Lai SC, Tsai JT. Gamma Knife Perfexion® radiosurgery and endo diode laser thermotherapy for choroidal melanoma with technical analysis: A case report. Oncology Letters. 2018 Jan; 15(1): 91–98. (SCI)
- Li MH, Huang SF, Chang CC, Lin JC, Tsai JT. Variations in dosimetric distribution and plan complexity with collimator angles in hypofractionated volumetric arc radiotherapy for treating prostate cancer. Journal of Applied Clinical Medical Physics. 2018 Mar;19(2):93-102. (SCI)
- Li MH, Tsai JT, Ting LL, Lin JC, Liu YC. Comparison of Thoracic Radiotherapy Efficacy Between Patients With and Without EGFR-mutated Lung Adenocarcinoma. In Vivo. 2018 Jan-Feb;32(1):203-209.
- Cheng HW, Lo WL, Kuo CY, Su YK, Tsai JT, Lin JW, Wang YJ, Pan DH. Forward treatment planning techniques to reduce the normalization effect in Gamma Knife radiosurgery. J Appl Clin Med Phys. 2017 Nov;18(6):114-122. doi: 10.1002/acm2.12193. Epub 2017 Sep 27. (SCI)
- Lee HL, Kuo CC, Tsai JT, Chen CY, Wu MH, Chiou JF. Magnetic Resonance-Guided Focused Ultrasound Versus Conventional Radiation Therapy for Painful Bone Metastasis: A Matched-Pair Study. Journal of Bone & Joint Surgery – American. 2017;(99):1572–1578.(SCI)
- Kuo CY, Tsai YC, Shiau AC, Cheng HW, Yu HW, Su YK, Tsai JT. Evaluation of Clinical Application and Dosimetric Comparison of Treatment Plans of Gamma Knife and CyberKnife in Treating Arteriovenous Malformations. Stereotact Funct Neurosurg. 2017;95(3):142-148. (SCI)
- Lin JC, Tsai JT, Chen LJ, Li MH, Liu WH. Compared planning dosimetry of TOMO, VMAT and IMRT in rectal cancer with different simulated positions. Oncotarget. 2017; 8(26): 42020-42029. (SCI)
- Chen CY, Lee LM, Yu HW, Lee SP, Lee HL, Lin YW, Wen YC, Chen YJ, Chen CP, Tsai JT. Dosimetric and radiobiological comparison of Cyberknife and Tomotherapy in stereotactic body radiotherapy for localized prostate cancer. Journal of X-Ray Science and Technology. 2017;25(3):465-477. (SCI)
- Hsu SM, Hung CH, Liao YJ, Fu HM, Tsai JT, Huang YH, Huang DY. Feasibility Study on Applying Radiophotoluminescent Glass Dosimeters for CyberKnife SRS Dose Verification. PLoS One. 2017; 12(1):e0169252. (SCI)
- Huang TW, Kuo KN, Chen KH, Chen C, Hou WH, Lee WH, Chao TY, Tsai JT, Su CM, Huang MT, Tam KW. Recommendation for axillary lymph node dissection in women with early breast cancer and sentinel node metastasis: A systematic review and meta-analysis of randomized controlled trials using the GRADE system. International Journal of Surgery. 2016;(34):73-80. (SCI)
- Lin JC, Jen YM, Li MH, Chao HL, Tsai JT. Comparing outcomes of stereotactic body radiotherapy with intensity-modulated radiotherapy for patients with locally advanced unresectable pancreatic cancer. Eur J Gastroenterol Hepatol .2015 ;(27):259-264.(SCI)
- Lin JC, Tsai JT, Chang CC, Jen YM, Li MH, Liu WH. Comparing Treatment Plan in All Locations of Esophageal Cancer Volumetric Modulated Arc Therapy versus Intensity-Modulated RadiotherapyComparing outcomes of stereotactic body radiotherapy withintensity-modulated radiotherapy for patients with locallyadvanced unresectable pancreatic cancer. Medicine (Baltimore). 2015 ;94(17):e750. (SCI)
- Chien-Min Lin, Jo-Ting Tsai, Chen Kuei Chang, Juei-Tang Cheng, Jia-Wei Lin. Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats. Drug design, development and therapy.2015;(9):4709-4717. (SCI)
- Lin JC, Jen YM, Li MH, Chao HL, Tsai JT. Comparing outcomes of stereotactic body radiotherapy with intensity-modulated radiotherapy for patients with locally advanced unresectable pancreatic cancer . Eur J Gastroenterol Hepatol .2015 ;(27):259-264.(SCI)
- Kuo CY, Liou TH, Chan KH, Chi WC, Escorpizo R, Tsai JT. Functioning and Disability Analysis of Patients with Traumatic Brain Injury and Spinal Cord Injury by Using the World Health Organization Disability Assessment Schedule 2.0 Int. J. Environ. Res. Public Health 2015(12):4116-4127. (SCI)
- Chiang MF, Chen HH, Chi CW, Sze CI, Hsu ML, Tsai JT. Modulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells Exp Biol Med 2015.(SCI)
