Jinping Lai

• Zhang D, Hart J, Ding X, Zhang X, Feely M, Yassan L, Alpert L, Soldevila-Pico C, Zhang X, Liu X and Lai J. Histologic patterns of anti-PD-1 therapy-induced liver injury. Gastroenterol Rep. 2019 (in press)
• Zhang D, Liao X, Tang Y, Meyer RG, Van Dyke DL, Liu X, Islam MN, and Lai J.Warthin-like Mucoepidermoid Carcinoma of the Parotid Gland: Unusual morphology and diagnostic pitfalls. Anticancer Res, 2019 (in press).
• Bril F, Biernacki DM, Lomonaco R, Kalavalapalli S,  SubbarayanS, Lai JSuman A, Orsak B,  Hecht J, Finch J, and Cusi K. Pathophysiology/Complications - Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care2019 (in press).
• Bril F, Leeming DJ, Karsdal M, Kalavalapalli S,  Barb D, Lai J,Rabe M, and Cusi K. Novel Communications in Diabetes - Use of Plasma Fragments of Pro-peptide of Type III, V, and VI Procollagen for the Detection of Liver Fibrosis in Type 2 Diabetes. Diabetes Care2019 (in press).
• Hu M, Tang Y, Long G, Zhang D, Kresak JL, and Lai J. Primary Extracranial Meningioma of Mastoid in a Patient with History of Skin Squamous Cell Carcinoma, Lung Adenocarcinoma, and Prostatic Carcinoma.Anticancer Res, 2019 (in press).
• Lai J, Kresak JL, Cao D, Zhang D, Zhang S, Gonzalo DH, Wang H, Liu X, and Fan X. Gastric plexiform fibromyxoma: a great mimic of gastrointestinal stromal tumor (GIST) and diagnostic pitfalls. J Surg Res, 2019 Jul;239:76-82. DOI: 10.1016/j.jss.2019.01.062. Epub 2019 Feb 26. PubMed PMID: 30822694.
• Dinarvand P, Davaro EP, Doan JV, Ising ME, Evans NR, Phillips NJ, Lai J, Guzman MA. Familial Adenomatous Polyposis Syndrome: An Update and Review of Extraintestinal Manifestations. Arch Pathol Lab Med. 2019 May 9. doi: 10.5858/arpa.2018-0570-RA. [Epub ahead of print] PubMed PMID: 31070935. 
• Upadhyaya JD, Fitzpatrick SG, Cohen DM, Bilodeau EA, Bhattacharyya I, Lewis JS Jr, Lai J, Wright JM, Bishop JA, Leon ME, Islam MN, Seethala R, Padilla RJ, Carlos R, Müller S, Thompson LDR. Inter-observer Variability in the Diagnosis of Proliferative Verrucous Leukoplakia: Clinical Implications for Oral and Maxillofacial Surgeon Understanding: A Collaborative Pilot Study. Head Neck Pathol. 2019 Apr 10. doi: 10.1007/s12105-019-01035-z. [Epub ahead of print] PubMed PMID: 30972634. 
• Jin Z, Zhang D, Zhang Q, Lai J, Akki A, Esnakula A, Kresak J, Gonzalo DH, Draganov PV, Xie H, Liu X. Desmoplasia and Detached Papillae in Early Esophageal Adenocarcinoma: A Histologic Study on Endoscopic Submucosal Dissection Specimens. Gastroenterology Res. 2019 Apr;12(2):72-77. doi: 10.14740/gr1154. Epub 2019 Apr 7. PubMed PMID: 31019616; PubMed Central PMCID: PMC6469900. 
• Al-Taee A, Gill A, Mahon S, Lai J, Jallad B. Gallbladder Adenocarcinoma as the First Manifestation of Germline BRCA1 Mutation. J Gastrointest Cancer. 2019 Mar;50(1):147-150. DOI: 10.1007/s12029-017-9995-9. PubMed PMID: 28785956. 
• Chen L, Himmelfarb EA, Sun M, Choi EK, Fan L, Lai J, Kim CJ, Xu H, and Wang HL.Immunostaining Patterns of Posttransplant Liver Biopsies Using Two Anti-C4d Antibodies.Applied Immunohistochemistry& Molecular Morphology, 2019 Feb 22. DOI: 10.1097/PAI.0000000000000723. [Epub ahead of print] PubMed PMID: 30807308. 
• Bril F, McPhaul MJ, Caulfield MP, Castille JM, Poynard T, Soldevila-Pico C, Clark VC, Firpi-Morell RJ, Lai J, Cusi K.Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.J Investig Med. 2019 Feb; 67(2):303-311. DOI: 10.1136/jim-2018-000864. PMID:30309884
  
• Hou R, Nayak R, Pincus SM, Lai J, Omran LM, Al-Kaade S, Abate G. Esophageal Mycobacterium avium-intracellulare infection in a bone marrow transplant patient: Case report and literature review.Transpl Infect Dis. 2019Feb; 21(1): e13019. DOI: 10.1111/tid.13019. [Epub ahead of print] PMID:30371970 
• Zhang D, Williams WD, Lai J.An Unusual Case of Cecal Mesenteric Dedifferentiated Liposarcoma Involving the Ileocolic Artery Resected by Right Hemicolectomy.Anticancer Res. 2019 Jan;39(1):487-490. DOI: 10.21873/anticanres.13138. PMID: 30591499.
• Zhang D, Glover SC, Liu W, Liu X, Lai J.Small Bowel Pyogenic Granuloma With Cytomegalovirus Infection in a Patient With Crohn's Disease (Report of a Case and Review of the Literature).In Vivo. 2019 Jan-Feb;33(1):251-254. DOI: 10.21873/invivo.11468. PMID:30587632.
  
• Hu M, Liu W, Yin F, Zhang D, Liu X, Lai J.Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity With Poor Prognosis and Review of the Literature. Gastroenterology Res. 2018 Dec;11(6):430-435. doi: 10.14740/gr1097. Epub 2018 Dec 17. PMID:30627268
  
• Yin F, Piao J, Liu X, Lai J. Foamy Histiocyte-like Esophageal Adenocarcinoma: Unusual Morphology and Diagnostic Pitfalls. Anticancer Res. 2018 Oct;38(10):5999-6002. doi: 10.21873/anticanres.12948. PMID:30275231
  
• Zhao M, Sun L, Lai JZ, Shi H, Mei K, He X, Jin X, Lai J, Cao D.Expression of RNA-binding protein LIN28 in classic gastric hepatoid carcinomas, gastric fetal type gastrointestinal adenocarcinomas, and hepatocellular carcinomas: An immunohistochemical study with comparison to SALL4, alpha-fetoprotein, glypican-3, and Hep Par1.Pathol Res Pract. 2018 Oct;214(10):1707-1712. doi: 10.1016/j.prp.2018.07.037. Epub 2018 Aug 2. PMID:30196987
• Lu J, Firpi-Morell RJ, Dang LH, Lai J, Liu X. An Unusual Case of Gastritis in One Patient Receiving PD-1 Blocking Therapy: Coexisting Immune-Related Gastritis and Cytomegaloviral Infection.Gastroenterology Res. 2018 Oct;11(5):383-387. doi: 10.14740/gr1068w. Epub 2018 Oct 1.PMID:30344812
• Jiang P, Gu L, Zhou Y, Zhao Y and Lai J. Synchronous Laryngeal Squamous Cell Carcinoma and Intrahepatic Cholangiocarcinoma Present in an Obese Male with Poor Prognosis. Anticancer Res 2018 Sep; 38(9):5547-5550. doi: 10.21873/anticanres.12890.PMID:30194215
• Liu W, Zhang D, Tan SA, Liu X, and Lai J. Sigmoid Colon Adenocarcinoma with Isolated Loss of PMS2 Presenting in a Patient with Synchronous Prostate Cancer with Intact MMR: Diagnosis and Analysis of the Family Pedigree. Anticancer Res. 2018 Aug;38(8):4847-4852. doi: 10.21873/anticanres.12796. PMID:30061258
  
• Alotaiby F, Song F, Boyce BJ, Cao D, Zhao Y, and Lai J. Unusual Papillary Squamous Cell Carcinoma of the Tip of Tongue Presenting in a Patient Status Post Heart Transplant. Anticancer Res. 2018 Jul;38(7):4203-4206. doi: 10.21873/anticanres.12715. PubMed PMID: 29970551.
• Yang C, Sun L, Zhang L, Zhou L, Niu D, Cao W, Li Z, Huang X, Kang Q, Jia L, Platik M, Liu X, Lai J, Cao D. SATB2 Shows Different Profiles Between Appendiceal Adenocarcinomas Ex Goblet Cell Carcinoids and Appendiceal/Colorectal Conventional Adenocarcinomas: An Immunohistochemical Study With Comparison to CDX2.Gastroenterology Res. 2018 Jun;11(3):221-230. doi: 10.14740/gr1015w. Epub 2018 May 31. PubMed PMID: 29915633; PubMed Central PMCID: PMC5997472.
  
• Panuganti B, Chang ES, Helm CW, Schwartz T, Hsueh EC, Piao J, Lai J, Veerapong J. Cytoreductive Surgery and Normothermic Intraperitoneal Chemotherapy for Signet Ring Cell Appendiceal Adenocarcinoma With Peritoneal Metastases in the Setting of Cirrhosis.Gastroenterology Res. 2018 Jun;11(3):247-251. doi: 10.14740/gr1029w. Epub 2018 May 31. PubMed PMID: 29915638; PubMed Central PMCID: PMC5997481. 
  
• Kantor M,Eiseler S, Schiller A, Hughes S, Liu X, and Lai J. Pancreatic and Gastric Heterotopic Tissue Presenting as a Symptomatic Gallbladder Mass: A Case Report and Literature Review. Clin Res Hepatol Gastroenterol 2018 Apr 4 pii: S2210-7401(18)30024-X. doi: 10.1016/j.clinre.2018.02.001. [Epub ahead of print] PMID: 29625925
  
• Xiang X, Zhang H, Piao J, Muthusamy S, Wang L, Deng Y, Zhang W, Kuaang R, Billadeau DD, Huang S, Lai J, Urrutia R and Kang N. Vasodilator-Stimulated Phosphoprotein Promotes Liver Metastasis of Gastrointestinal Cancer by Activating a Novel ß1-Integrin-FAK-YAP1/TAZ Signaling Pathway. npj Precision Oncology, 2018; 2:2. Doi:10. 1038/s41698-017-0045-7
  
• Meeks M, Grace S, Montenegro G, Schoen M, Carpenter M, Lai JP, and Poddar N. Perianal Basal Cell Carcinoma. J Gastrointest Cancer, 2018 Apr 2. doi: 10.1007/s12029-018-0092-5. [Epub ahead of print] No abstract available. PMID:29607468
  
• Hu M, Trevino J, Yang L, Cao D, Liu X, and Lai J. Primary Gastric EBV-positive diffuse large B cell lymphoma (DLBCL) of the elderly with plasmablastic differentiation. In Vivo, 2018 Mar-Apr;32(2):413-417. PMID:29475930
• Zhang W, De D, Mohammed KA, Munigala S, Chen G, Lai JP, Bacon BR. New Scoring Classification for Primary Biliary Cholangitis–Autoimmune Hepatitis Overlap Syndrome. Hepatol Commun. 2018 Feb 20;2(3):245-253. doi: 10.1002/hep4.1148. eCollection 2018 Mar. PMID:29507900
  
• Hemmerich A, Shaar M, Burbridge R, Guy CD, McCall SJ, Cardona DM, Zhang X, Lai J, and Zhang X. Metastatic Renal Cell Carcinoma as Solitary Subcentimeter Polypoid Gastric Mucosal Lesions: Clinicopathologic Analysis of Five Cases. Gastroenterol Res. 2018 Feb;11(1):25-30. doi: 10.14740/gr952w. Epub 2018 Feb 23. PMID: 29511402
  
• Riverso M, Chang M, Soldevila-Pico C, Lai J, Liu X. Histologic Characterization of Kratom Use-Associated Liver Injury.Gastroenterology Res. 2018 Feb;11(1):79-82. doi: 10.14740/gr990e. Epub 2018 Feb 23. PMID:29511414
  
• Hammami MB, Talkin R, Al-Taee AM, Schoen MW, Goyal SD, Lai JP. Autologous Graft-Versus-Host Disease of the Gastrointestinal Tract in Patients With Multiple Myeloma and Hematopoietic Stem Cell Transplantation.Gastroenterol Res. 2018 Feb;11(1):52-57. doi: 10.14740/gr925w. Epub 2018 Feb 23. PMID:29511407
  
• Zhou W, Saam T, Zhou Y, Trevino J, Liu X, Cao D and Lai J. Pancreatic Mucinous Cystic Neoplasm Communicating with Main Pancreatic Duct: An Unrecognized Presentation of Pancreatic Mucinous Neoplasm?Anticancer Res 2017 Dec;37(12):7017-7021.PMID:29187489
  
• Meeks M, Grace S, Veerapong J, Chen Y, Cao D, Zhou Y, Lai JP. Primary Angiosarcoma of the Pancreas.J Gastrointest Cancer. 2017Dec;48(4):369-372. doi: 10.1007/s12029-016-9837-1. PMID:27228987
  
• Peng H, Ning H, Wang Q, Lu W, Chang Y, Wang TT, Lai J, Kolattukudy PE, Hou R, Hoft DF, Dykewicz MS, Liu J. MCPIP1 controls allergic airway inflammation by suppressing IL-5-producing Th2 cells through Notch/Gata3 pathway. J Allergy Clin Immunol. 2017, Oct 27. pii: S0091-6749(17)31654-8. doi: 10.1016/j.jaci.2017.09.031. [Epub ahead of print] PMID: 29111212
• Lee AA, Poddar N, Hammami MB, Veerapong J, Cao D, Lai JP. Gastric Spindle Cell Neuroendocrine Tumor Mimicking Gastrointestinal Stromal Tumor: Unique Morphology and Diagnostic Pitfall.Anticancer Res. 2017 Oct;37(10):5893-5897. PMID:28982917
  
• Yang C, Sun L, Zhang L, Zhou L, Zhao M, Peng Y, Niu D, Li Z, Huang X, Kang Q, Jia L, Lai J, Cao D.  Diagnostic Utility of SATB2 in Metastatic Krukenberg Tumors of the Ovary: An Immunohistochemical Study of 70 Cases With Comparison to CDX2, CK7, CK20, Chromogranin, and Synaptophysin. Am J Surg Pathol. 2017 Sep 13. doi: 10.1097/PAS.0000000000000951. [Epub ahead of print] PMID:28914716
  
• Roberts RO, Kang YN, Hu C, Moser C, Wang S, Moore MJ, Graham R, Lai JP, Peterson RC, Roberts LR. Decreased Expression of Sulfatase 2 in the Brains of Alzheimer’s Disease Patients: Implications for Regulation of Neuronal Cell Signaling. J. Alzheimer Dis Rep. 2017 Sep;1(1): 115-124.DOI:10.3233/ADR-170028
  
• Poddar N, Ramlal R, Ravulapati S, Devlin S M, Gadani S, Vidal CI, Cao D, Befeler AS, LaiJ. Extrahepatic Metastasis of Hepatocellular Carcinoma Arising from a Hepatic Adenoma Without Concurrent Intrahepatic Recurrence. Curr Oncol.2017 Aug;24(4):e333-e336. doi: 10.3747/co.24.3494. Epub 2017 Aug 31.
  
• Al-Taee AM, Gremida AK, Cheung AC, Lai J, Neuschwander-Tetri B. An unusual case of cholestatic hepatitis. J Gastroenterol Hepatol Res. 2017 August 21; 6(4): 2411-2415. doi: 10.17554/j.issn.2224-3992.2017.06.714
  
• Al-Taee A, Gill A, Mahon S, Lai J, Jallad B.  Gallbladder Adenocarcinoma as the First Manifestation of Germline BRCA1 Mutation.J Gastrointest Cancer. 2017 Aug 8. doi: 10.1007/s12029-017-9995-9. [Epub ahead of print] PMID:28785956
  
• Cull S, Westrich DJ Jr, Bhatia R, Lai J, Befeler A. Multiple Myeloma Presenting as Acute Liver Failure. ACG Case Rep J. 2017 Jul 5;4:e85. doi: 10.14309/crj.2017.85. eCollection 2017. PMID:28706961
  
• Hammami MB, Chhaparia A, Piao J, Zhou Y, Hachem C, Lai J. Mixed Adenocarcinoma and Squamous Cell Carcinoma of Duodenum: A case report and Review of the Literature. Case Rep Gastroenterol. 2017; 11:402-410
  
• Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children.J Pediatr. 2017 Aug;187:141-146.e1. doi: 10.1016/j.jpeds.2017.03.007. Epub 2017 Mar 30. PMID:28366357
  
• Zhao M, Zhou L, Sun L, Song Y, Guo Y, Zhang X, Zhao F, Wang P, Yue J, Niu D, Li Z, Huang X, Kang Q, Jia L, Lai J, Cao D. GATA3 is a sensitive marker for primary genital extramammary paget disease: an immunohistochemical study of 72 cases with comparison to gross cystic disease fluid protein 15.Diagn Pathol. 2017 Jul 10;12(1):51. doi: 10.1186/s13000-017-0638-z. PubMed PMID: 28693610; PubMed Central PMCID: PMC5504764.
  

• CAPA-USCAP Best Platform Presentation Awrard (third place): Zhang D, Ding X, Feely M, Yassan L, Alpert L, Soldevila-Pico C, Hart J, Liu X and Lai J. Histology patterns of anti-PD-1 therapy-induced liver injury. Platform presentation at the USCAP Annual Meeting, Vancouver, Canada, March 17-23, 2018.
• CAPA Best Abstract award (first place): Jin Z, Zhang D, Lai J, Akki A, Esnakula A, Kresak JL, Gonzalo DH, Draganov PV, and Liu X. Detached Papillae in Early Esophageal Adenocarcinoma: an Unrecognized Histologic Feature. Poster presentation at the CAPA Annual Meeting, Vancouver, Canada, March 17-23, 2018.
  
• CAPA-Go Path Best Abstract Award: Piao J, Rutgers JK, Chen Y, Crawford S, Phillips N, Hou P, Kang N, and Lai JP. Vasodilator-Stimulated Phosphoprotein (VASP) Immunoreactivity Is Associated with Lymphovascular Invasion of Colorectal Adenocarcinoma (CRC) Leading to Liver and Lymph Node Metastases. At the USCAP Annual Meeting, Seattle, Washington, March 12-18, 2016.
  
• Distinguished Young investigator award- “Minimal invasive laser therapy for early stage laryngeal carcinoma”, the Ministry of Education, China, 2000 
  
• Distinguished Young Scientist award-“Diagnosis and treatment of nasopharyngeal carcinoma”, the Government of Hunan Province, 1999.
  
• Distinguished Young Investigator award-“Early diagnosis and photodynamic therapy for nasopharyngeal carcinoma”, the Ministry of Public Health, China, 1998.
  
• Second prize Award “Studies of operative methods for treatment of otorhinopharyngeal tumor invading the to skull base”, the Committee of Science and Technology of Hunan Province, China, in 1999, (No: 9913210).
  
• Third prize Award “Fiberoptic laryngosopic YAG laser therapy for diseases of the pharynx and larynx”, the Committee for Science and technology of Hunan Province, China, in 1998. (No: 9813224).
  
• Second prize award-“Basic and clinical studies of photodynamic therapy for nasopharyngeal carcinoma”, the Committee for Science and Technology of Hunan Province, China, in 1994. (No: 940162).
  
• Second prize award “The significance of early stage diagnosis of the specific EB virus DNA polymerase”, the Committee for Science and Technology of Hunan Province, China, in 1995. (No: 950144).

Ongoing research support

• UF CRC grant ($5000) (PI: Lai J, 2018). Biomarkers (PD-L1, Bim, CD11a and CD8) in predicting PD-1 treatment response in cancers. Role: Principal Investigator
• NIH/NIDDK Clinical trial  5U01DK061718-09 (PI: Neuschwander-Tetri) 2002-2019. NASH Clinical Research Network Continuing Review of Hyperinsulinemia and the Pathogenesis of NASH. The long-term objective of this cooperative agreement is to better understand the natural history, clinical correlates and treatment of NASH through participation in a multi-center clinical research network. Role: Co-Investigator 02/2016-05/2017 (10% NIH cap salary).
• Private agency/Foundation (Alpha-1 Foundation) (PI: Teckman J) 2014-2019. Alpha-1 antitrypsin deficiency adult clinical and genetic linkage study. Role: Co-investigator.
• St Louis University Doisy Fund for GI and Liver disease ($5000) (PI: Lai JP) 2015-2016. Role of SULF2 in pathogenesis of cirrhosis, hepatocellular carcinoma and cholangiocarcinoma. Role: Principal investigator.
• St Louis University Doisy Fund for GI diseases ($10000) (PI: Lai JP) 2015-2016. Expression of ATGL and PEDF in colorectal cancers. Role: Principal investigator.
• St.Louis University Doisy Fund for GI diseases ($75000) (PI: Lai J, 2016-2017). Biomarkers (PD-L1, Bim) in predicting PD-1 treatment response in cancers. Role: Principal Investigator.